Modifiable pathways in Alzheimer’s disease: Mendelian randomisation analysis

BMJ 2017;359:j5375

This study aims to determine which potentially modifiable risk factors, including socioeconomic, lifestyle/dietary, cardiometabolic, and inflammatory factors, are associated with Alzheimer’s disease.  The design of the study is a Mendelian randomisation study using genetic variants associated with the modifiable risk factors as instrumental variables.  The study concludes that the results provide support that higher educational attainment is associated with a reduced risk of Alzheimer’s disease.

Click here to read the full text paper.

Advertisements