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Low dose aspirin as adjuvant treatment for venous leg ulceration: pragmatic, randomised, double blind, placebo controlled trial (Aspirin4VLU)

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BMJ 2017;359:j5157

This randomized controlled trial aims to determine the effect of low dose aspirin on ulcer healing in patients with venous leg ulcers.  The participants included 251 adults with venous leg ulcers who could safely be treated with aspirin or placebo: 125 were randomised to aspirin and 126 to placebo.  The conclusion of the study suggests that the findings do not support the use of low dose aspirin as adjuvant treatment for venous leg ulcers.

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