The Sepsis Manual: 4th edition 2017 -2018

The Sepsis Trust, June 2018

Looks at the epidemiology of sepsis finding that while the recording of the number of cases of sepsis has improved and there is a better understanding of its impact on the NHS and society, we still have to estimate figures based on the best available data. Conservative estimates would suggest that we see at least 250,000 cases of sepsis in the UK each year, with at least 46,000 deaths and a direct cost to the NHS of at least £1.5 billion. The authors state that sepsis costs our society as much as £15.6 billion every year. It is highly likely that these numbers are significant under-estimates, since a proportion of the more than 1.5 million patients suffering severe infection in England every year are likely to have uncoded sepsis.

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