Guided graded exercise self-help plus specialist medical care versus specialist medical care alone for chronic fatigue syndrome (GETSET): a pragmatic randomised controlled trial

The Lancet, 22 June

Graded exercise therapy is an effective and safe treatment for chronic fatigue syndrome, but it is therapist intensive and availability is limited. This study aimed to test the efficacy and safety of graded exercise delivered as guided self-help.  The study finds that GES is a safe intervention that might reduce fatigue and, to a lesser extent, physical disability for patients with chronic fatigue syndrome. These findings need confirmation and extension to other health-care settings.

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Exercise therapy for chronic fatigue syndrome

Cochrane Database of Systematic Reviews, April 2017

The objective of this systematic review was to determine the effects of exercise therapy (ET) for patients with CFS as compared with any other intervention or control.  This review is an update of a previous Cochrane review from 2004, which showed that exercise therapy was a promising treatment for adults with CFS. Since the review, additional studies investigating the effectiveness and safety of exercise therapy for patients with CFS have been published.

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US panel proposes new name and diagnostic criteria for chronic fatigue syndrome

BMJ, 10 February 2015

The condition known as myalgic encephalitis (ME) or chronic fatigue syndrome (CFS) is a serious, chronic multisystem disease that can cause significant impairment and disability, an expert panel convened by the US Institute of Medicine has concluded in a new report…

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