Prescribing anti-epileptic drugs for people with epilepsy and intellectual disability: (College Report CR206)

Royal College of Psychiatrists, November 2017

This report addresses the extremely important area of epilepsy in the field of intellectual disability (ID), also known as learning disability. Epilepsy and ID are two conditions that carry stigma and can lead to social isolation. An individual who experiences both these problems faces huge challenges.

Click here to view the report.

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Risk of neonatal drug withdrawal after intrauterine co-exposure to opioids and psychotropic medications: cohort study

BMJ 2017;358:j3326

This observational cohort study aims to assess the impact of in utero co-exposure to psychotropic medications and opioids on the incidence and severity of neonatal drug withdrawal.  The study concludes that during pregnancy, the use of psychotropic medications in addition to prescription opioids is common, despite a lack of safety data. The current findings suggest that these drugs could further increase the risk and severity of neonatal drug withdrawal.

Click here to access the full text paper.

Enhancing the use of scientific evidence to judge the potential benefits and harms of medicines

The Academy of Medical Sciences, June 2017

This report highlights the significant difficulties patients and some healthcare professionals face in using evidence from research to judge the benefits and harms of medicines, and calls for concerted action to improve the information patients receive.The report calls for a range of actions including significant improvements to patient information leaflets, better use of medical appointments and a bigger role for NHS Choices as the ‘go to’ source of trusted information online for patients and carers, as well as healthcare professionals.

Click here to view the report

Important message: British National Formulary (BNF70) and the Children’s British National Formulary (BNFC 2015)

British National Formulary, February 2016

Please be advised that due to errors contained within the previously distributed hard copy version of the British National Formulary (BNF70) and the BNFC (2015) that serious patient safety incidents have been reported through the national reporting and learning system (NRLS).

An adhesive addendum will be produced at the end of February to be placed on the front of all hard copies and where Trusts have distributed copies in house, they should consider re-calling all copies.

All Practitioners are reminded that the most current up to date accurate version of the BNF and BNFC can be accessed via the electronic site here.

You can also access this via the following links

·         Via Medicines complete – please click here for further details

·         Via NICE evidence summaries – please click here

·         Via NICE BNF app – please click here for further details

Use of combined oral contraceptives and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases

BMJ, 26 May 2015

This study, designed as two nested case control studies, aims to investigate the association between use of combined oral contraceptives and risk of venous thromboembolism, taking the type of progestogen into account.  The study concluded that inn these population based, case-control studies using two large primary care databases, risks of venous thromboembolism associated with combined oral contraceptives were, with the exception of norgestimate, higher for newer drug preparations than for second generation drugs.

Click here to view the full text paper.