LCFT Research Bulletin – October 2018

Lancashire Care, October 2018

Please click here to view the latest Lancashire Care Research bulletin to see research and journal articles produced by staff in the Trust.


World Alzheimer Report 2018: The State Of The Art Of Dementia Research: New Frontiers

Alzheimer’s Disease International, September 2018

Alzheimer’s Disease International report that looks at a broad cross section of research areas including basic science; diagnosis; drug discovery; risk reduction and epidemiology. With the continued absence of a disease modifying treatment, the report also features progress, innovation and developments in care research. It highlights an urgent need for increased and sustainable funding for dementia research.

Click here to view the full report.

Use of haloperidol versus atypical antipsychotics and risk of in-hospital death in patients with acute myocardial infarction: cohort study

BMJ 2018;360:k1218

This cohort study aims to compare the risk of in-hospital mortality associated with haloperidol compared with atypical antipsychotics in patients admitted to hospital with acute myocardial infarction.

The results of the study suggest a small increased risk of death within seven days of initiating haloperidol compared with initiating an atypical antipsychotic in patients with acute myocardial infarction. Although residual confounding cannot be excluded, this finding deserves consideration when haloperidol is used for patients admitted to hospital with cardiac morbidity.

Click here to access this paper.

Forward thinking: NIHR research on support for people with severe mental illness

National Institute of Health Research, March 2018

Report from the National Institute of Health Research detailing 30 published studies funded by the National Institute of Health Research (NIHR) and additional examples of ongoing research that  provides an overview of recent research funded by the NIHR on the support for people living with severe mental illness.  The focus of research is on:

  • Support early detection and intervention
  • Focus on crisis care in terms of location, settings and practice
  • Stabilising, managing mental and physical health

Supporting recovery, self management and engagement.

Click here to view the full report.

Impact of person-centred care training and person-centred activities on quality of life, agitation, and antipsychotic use in people with dementia living in nursing homes: A cluster-randomised controlled trial

PLOS Medicine, February 6, 2018

This study aimed to evaluate the efficacy of a person-centred care and psychosocial intervention incorporating an antipsychotic review, WHELD, on QoL, agitation, and antipsychotic use in people with dementia living in nursing homes, and to determine its cost.

Click here to view the paper.