Schizophrenia Bulletin – September 2017

The September issue of Schizophrenia Bulletin has been published.  This edition includes articles on motor systems in relation to schizophrenia and psychosis, and psychotic experiences in the context of police victimization.

Click here to view the table of contents and access full text articles.  You will need to login with your LCFT OpenAthens account.

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Five years of specialised early intervention versus two years of specialised early intervention followed by three years of standard treatment for patients with a first episode psychosis: randomised, superiority, parallel group trial in Denmark (OPUS II)

BMJ 2017;356:i6681 – January 2017

This randomised, superiority, parallel group trial aims to compare the effects of five years of specialised early intervention (SEI) treatment for first episode schizophrenia spectrum disorder with the standard two years of SEI plus three years of treatment as usual.

Click here to access the full text paper.

 

Occupational therapy delivered by specialists versus non-specialists for people with schizophrenia

Cochrane Database of Systematic Reviews, October 2016

This review protocol was co-written by Graeme Reid, Consultant Clinical Psychologist at Lancashire Care NHS Foundation Trust.

The objectives are to examine the effects of occupational therapy delivered by occupational therapists compared to occupational therapy delivered by any other person for people with schizophrenia. Our secondary objectives are to determine whether the response differs by specific type (e.g. hospital versus non-hosptial setting), intensity (e.g. more therapist contact time or more frequent task repetition), or duration of occupational therapy.

Click here to access this protocol.

Antidepressant Controlled Trial For Negative Symptoms In Schizophrenia (ACTIONS): a double-blind, placebo-controlled, randomised clinical trial

National Institute of Health Research, April 2016

Negative symptoms of schizophrenia represent deficiencies in emotional responsiveness, motivation, socialisation, speech and movement. When persistent, they are held to account for much of the poor functional outcomes associated with schizophrenia. There are currently no approved pharmacological treatments. While the available evidence suggests that a combination of antipsychotic and antidepressant medication may be effective in treating negative symptoms, it is too limited to allow any firm conclusions.

This trial aims to establish the clinical effectiveness and cost-effectiveness of augmentation of antipsychotic medication with the antidepressant citalopram for the management of negative symptoms in schizophrenia.

Click here to access the full text paper.

Clinical effectiveness and cost-effectiveness of body psychotherapy in the treatment of negative symptoms of schizophrenia: A multicentre randomised controlled trial

NIHR Health Technology Assessment programme, February 2016

The negative symptoms of schizophrenia significantly impact on quality of life and social functioning, and current treatment options are limited. In this study the clinical effectiveness and cost-effectiveness of group body psychotherapy as a treatment for negative symptoms were compared with an active control.

Click here for more information and to download the full text article.

A ‘smart’ way to spot schizophrenia signs

BBC News, 31 October 2015

Emily Eisner, PhD Student at the University of Manchester is currently completing a research project, ExPRESS 2 in Adult Mental Health and Early Intervention Services at Lancashire Care Foundation Trust.  She has recently had an article about the study published on the BBC news website.

Click here to read her article.