Low dose aspirin as adjuvant treatment for venous leg ulceration: pragmatic, randomised, double blind, placebo controlled trial (Aspirin4VLU)

BMJ 2017;359:j5157

This randomized controlled trial aims to determine the effect of low dose aspirin on ulcer healing in patients with venous leg ulcers.  The participants included 251 adults with venous leg ulcers who could safely be treated with aspirin or placebo: 125 were randomised to aspirin and 126 to placebo.  The conclusion of the study suggests that the findings do not support the use of low dose aspirin as adjuvant treatment for venous leg ulcers.

Click here to view the full text paper.


Stay up to date with KnowledgeShare

The Gosall Library, December 2017

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KnowledgeShare is an online web-based current awareness system that is NHS OpenAthens password protected. We will create a profile of you in the system detailing your interests. Our KnowledgeShare notifications will be highly personalised and targeted to you.  Focusing on evidence that will change practice, and the latest publications on quality, safety, education and the patient experience, our aim is to bring you what you need to know and no more.

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British Journal of Healthcare Assistants – December 2017

The December edition of British Journal of Healthcare Assistants has been published.  This issue includes articles on the RCN guidance on infection prevention and the rare health conditions: diabulimia, precocious puberty and intersex/hermaphrodite.

Click here to view the table of contents.

Click here to request an article from the Library.

Modifiable pathways in Alzheimer’s disease: Mendelian randomisation analysis

BMJ 2017;359:j5375

This study aims to determine which potentially modifiable risk factors, including socioeconomic, lifestyle/dietary, cardiometabolic, and inflammatory factors, are associated with Alzheimer’s disease.  The design of the study is a Mendelian randomisation study using genetic variants associated with the modifiable risk factors as instrumental variables.  The study concludes that the results provide support that higher educational attainment is associated with a reduced risk of Alzheimer’s disease.

Click here to read the full text paper.

A framework for mental health research

Department of Health, December 2017

This framework provides a collective view of how mental health research should develop in the UK over the next decade. It sets out a structure to improve co-ordination and strengthen the focus on areas where mental health research is likely to translate into significant health benefit.

Click here to view the guidance.

Improving Lives: The Future of Work, Health and Disability

Department of Work and Pensions, December 2017

This paper that establishes how government, employers, charities, healthcare providers and local authorities will work to break down employment barriers for disabled people and people with health conditions over the next ten years. The actions outlined for health services focus on ensuring that health professionals are ready to talk about health barriers to work, timely access to appropriate treatments, and effective occupational health services accessible by all in work.

Click here to view the full report.

We change the world: What can we learn from global social movements for health?

Nesta, December 2017

This report presents actionable ways to grow social movements based on the practical experience of over 40 people representing four social movements.  It finds social movements:

  • Grow in influence by engaging the right people in the right places at the right time
  • Focus on an important set of early actions including mobilising people, experimenting with effective strategies, deploying assets and resources creatively
  • Understand the value of cultivating a diverse set of voices and the unique experiences, skills and interests they bring
  • Make smart trade-offs about where and how to invest their energy in relationships to achieve the highest level of influence and impact

This report provides conversation starters about what learnings might be applicable to movements in the UK and to broader movements affecting the social determinants of health.

Click here to view the full report.

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