Maternal use of oral contraceptives and risk of birth defects in Denmark: prospective, nationwide cohort study

BMJ, 6 January 2016

This prospective cohort study aims to research whether oral contraceptive use around the time of pregnancy onset is associated with an increased risk of major birth defects?

The study finds that oral contraceptive exposure just before or during pregnancy does not appear to be associated with an increased risk of major birth defects.

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Use of combined oral contraceptives and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases

BMJ, 26 May 2015

This study, designed as two nested case control studies, aims to investigate the association between use of combined oral contraceptives and risk of venous thromboembolism, taking the type of progestogen into account.  The study concluded that inn these population based, case-control studies using two large primary care databases, risks of venous thromboembolism associated with combined oral contraceptives were, with the exception of norgestimate, higher for newer drug preparations than for second generation drugs.

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